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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Eaker, Chris | SP | Free Agent | 30 | 04/05/2020 | Amarillo | USA | Left | Left | 6' 0" | 200 lbs | - |
| Ealy, Vince | SS | Texas Rangers | 36 | 09/15/2014 | Arlington | USA | Switch | Right | 6' 4" | 200 lbs | $18,000,000 |
| Eaton, Tommie | 3B | Seattle Mariners | 38 | 06/12/2012 | Sacramento | USA | Right | Right | 6' 6" | 205 lbs | - |
| Edlin, Jimmy | SP | Houston Astros | 26 | 06/13/2024 | Galveston | USA | Left | Left | 6' 2" | 200 lbs | $675,000 |
| Edwards, Harry | RP | Free Agent | 18 | 04/27/2032 | Great Yarmouth | ENG | Right | Left | 6' 0" | 175 lbs | - |
| Edwards, Jerry | 1B | Free Agent | 16 | 03/19/2034 | Milwaukee | USA | Switch | Right | 6' 5" | 200 lbs | - |
| Edwards, Miles | SP | Chicago Cubs | 26 | 03/25/2024 | Columbus | USA | Right | Right | 6' 0" | 190 lbs | $1,200,000 |
| Eguchi, Hidekazu | CF | Baltimore Orioles | 17 | 04/24/2033 | Ryotsu | JPN | Right | Right | 6' 0" | 165 lbs | - |
| Ehret, Kyle | RP | Free Agent | 36 | 03/05/2014 | Allentown | USA | Right | Right | 6' 2" | 200 lbs | - |
| Eismann, Marc | SP | Milwaukee Brewers | 25 | 07/09/2025 | Greenfield | USA | Left | Left | 6' 2" | 200 lbs | $675,000 |
| Eisner, Warren | 3B | Chicago Cubs | 32 | 04/25/2018 | Oberlin | USA | Switch | Right | 6' 0" | 200 lbs | $5,500,000 |
| Eldridge, Brian | CL | Free Agent | 16 | 08/31/2034 | Meadow Lake | USA | Switch | Right | 6' 4" | 180 lbs | - |
| Eli, Arturo | SP | New York Yankees | 26 | 01/02/2024 | Bachaquero | VEN | Left | Left | 6' 2" | 200 lbs | $7,420,000 |
| Elizondo, Nick | LF | San Diego Padres | 17 | 08/05/2033 | Cueto | CUB | Right | Right | 5' 10" | 170 lbs | - |
| Ellis, Rick | SS | Seattle Mariners | 28 | 08/13/2022 | Bellevue | USA | Right | Right | 6' 0" | 200 lbs | $675,000 |
| Emchenko, Marko | SP | Boston Red Sox | 33 | 05/13/2017 | Cherkasy | UKR | Left | Left | 6' 2" | 200 lbs | $3,000,000 |
| Encinias, Billy | C | Free Agent | 38 | 09/08/2012 | Brooklyn | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Engelhardt, Justin | 3B | Free Agent | 39 | 04/10/2011 | Irvine | USA | Right | Right | 6' 1" | 195 lbs | - |
| Enriquez, Melvin | LF | St. Louis Cardinals | 25 | 04/13/2025 | Villa del Rosario | VEN | Right | Right | 6' 3" | 200 lbs | $3,546,200 |
| Erlykov, Anton | RP | Washington Nationals | 26 | 02/23/2024 | Druzhny | BLR | Left | Left | 6' 1" | 205 lbs | $675,000 |
| Eronilde, Trystão | SP | Free Agent | 17 | 03/27/2033 | Valencia | VEN | Right | Right | 6' 4" | 185 lbs | - |
| Erwin, Dave | SP | Free Agent | 18 | 03/15/2032 | San Antonio | USA | Left | Left | 6' 3" | 180 lbs | - |
| Escalante, Raul | RP | Free Agent | 18 | 04/08/2032 | Castelldefels | ESP | Left | Left | 6' 2" | 180 lbs | - |
| Escue, Mark | SP | Free Agent | 17 | 10/14/2033 | Wyandanch | USA | Right | Left | 6' 2" | 180 lbs | - |
| Esini, Lucan | CF | San Francisco Giants | 27 | 08/23/2023 | Vatican City | VCY | Right | Right | 6' 4" | 205 lbs | $8,936,000 |
| Espinal, Edwin | RP | New York Yankees | 28 | 09/03/2022 | San Diego | USA | Right | Right | 6' 0" | 195 lbs | $675,000 |
| Esteves, Nick | CF | Free Agent | 34 | 02/01/2016 | Santo Domingo | DOM | Right | Right | 6' 5" | 200 lbs | - |
| Estrada, Gilberto | SP | Chicago Cubs | 18 | 01/15/2032 | Juarez | MEX | Right | Right | 5' 11" | 170 lbs | - |
| Estrada, Juan | RP | Houston Astros | 26 | 07/13/2024 | Durango | MEX | Right | Right | 6' 0" | 200 lbs | $675,000 |
| Estrada, Vinny | C | Milwaukee Brewers | 25 | 01/17/2025 | Cuautitlan Izcalli | MEX | Right | Right | 6' 5" | 205 lbs | $675,000 |
| Eubanks, Mike | C | Free Agent | 18 | 06/28/2032 | Swansea | USA | Right | Right | 6' 1" | 175 lbs | - |
| Evans, Matt | SP | Free Agent | 36 | 08/16/2014 | Seattle | USA | Right | Right | 6' 4" | 205 lbs | - |
| Ezzell, Justin | RP | Houston Astros | 28 | 09/02/2022 | Phoenix | USA | Right | Right | 6' 0" | 200 lbs | $1,600,000 |
